Journal Watch - Peritoneal Dialysis

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  • Glucose and Peritonitis

    A prospective, longitudinal cohort study followed 105 PD patients for up to 5 years (mean of 23 months). Higher glucose exposure significantly predicted peritonitis, and patients with more residual kidney function also had a significantly longer time to first bout of peritonitis. Read the abstract. The authors suggest using the lowest concentration of glucose possible.

    Read the abstract » | (added 2020-03-16)

    Tags: Glucose Exposure, Peritoneal Dialysis, Peritonitis

  • Exercise in PD Patients and Residual Renal Function

    After a 12-week home-based exercise program was completed, researchers analyzed residual renal function among 13 patients who received usual care and 16 who had been in the exercise intervention group. Urinary liver-type fatty acid-binding protein and microalbumin-to-creatinine ratios were significantly lower in the exercise group, suggesting a possible benefit.

    Read the abstract » | (added 2020-02-19)

    Tags: Exercise, Renal Outcome, Residual Renal Function, Peritoneal Dialysis

  • PD Glucose Absorption and Lipid Profiles

    Lipid status was assessed at baseline and 12 month in 143 CAPD patients, 2/3 of whom used a daytime icodextrin exchange. No associations were found between glucose absorption, lipid profiles, or changes in serum lipids.

    Read the abstract » | (added 2020-02-19)

    Tags: Peritoneal Dialysis, Cholesterol, Glucose, Triglycerides

  • Comorbidities—but not Peritonitis—drove Mortality on PD

    Among 242 Turkish PD patients followed for up to 9 years, age over 65, diabetes, cancer, and heart failure were independent risk factors for death, but surprisingly peritonitis was not.

    Read the abstract » | (added 2020-02-19)

    Tags: Peritoneal Dialysis, Mortality, Patient Survival, Peritonitis, Technique Survival

  • PD—Controlling Volume to Reach Normal Hydration Protects the Heart

    Reanalysis of data from a multicenter, prospective, randomized controlled trial looked at fluid control in PD in 151 patients followed for a year. While most (120) reached normal hydration levels as measured by bioimpedance analysis, those who did not had significantly higher left atrial diameter—and a lower left ventricular ejection fraction at the end of the study.

    Read the abstract » | (added 2019-12-10)

    Tags: Fluid Management, Cardiovascular Risk, PD, Peritoneal Dialysis, Bioimpedance Spectroscopy

  • Higher Serum Phosphorus Predicts More Residual Function Loss—in Men Only

    A retrospective analysis of 1,245 CAPD patients followed for up to 11 years divided participants into tertiles based on their baseline serum phosphorus levels. One third of patients lost residual renal function (RRF) during the study, and those with the highest baseline phosphorus levels had a 51% higher risk of RRF loss than those in tertiles 1 and 2 combined. The risk of RRF loss was significantly higher for men.

    Read the abstract » | (added 2019-12-10)

    Tags: Serum Phosphorus, Renal Function Loss, Gender, Peritoneal Dialysis

  • Transplant Survival Better After PD Than Standard In-center HD

    Is there an advantage to PD over standard in-center HD for transplant graft survival? YES, suggests a 15-year retrospective study of 2,277 transplant recipients. Those who did PD prior to transplant were 34.5% more likely to survive, and had less frequent rejection. Living donor kidneys did best among patients who received transplants before starting dialysis—or did PD.

    Read the abstract » | (added 2019-11-16)

    Tags: Kidney Transplant, Modality, PD, HD, Hemodialysis, Peritoneal Dialysis

  • PD vs. Standard In-center HD for Quality of Life

    A 24-month observational study compared 45 standard HD and 30 PD patients, and assessed their quality of life, cognitive function, and depression at study start and every 12 months. Over the 24 months, PD patients had significant improvement in physical and social well-being—while HD patients stayed the same. Cognitive function held steady in PD patients—but declined in HD patients. Depression increased among those on standard HD—but not those on PD.

    Read the abstract » | (added 2019-11-16)

    Tags: Peritoneal Dialysis, Hemodialysis, Cognitive Function, Emotional Distress, Quality Of Life

  • BMI Alters Sodium Balance in PD

    In a review of 439 PD patients, those with more urine volume, protein nitrogen appearance rate, fewer comorbidities, and higher BMI had greater sodium losses.

    Read the abstract » | (added 2019-09-11)

    Tags: Peritoneal Dialysis, Sodium Removal

  • Glycated Albumin vs. HbA1c Predicts Mortality in PD Patients with Diabetes

    In patients on hemodialysis, glycated albumin (GA) reflects glycemic control and predicts all-cause mortality. A new retrospective, longitudinal observational study looked at GA in PD. Among 44 PD patients with diabetes matched to 88 HD patients with diabetes followed for 3 years, GA was a more precise way to measure glycemic control than hemoglobin A1c.

    Read the abstract » | (added 2019-09-11)

    Tags: Peritoneal Dialysis, All cause Mortality, Glycaemic Control, Glycated Albumin, Glycated Haemoglobin