Journal Watch - Angiogenesis

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  • Glucose Degradation Product (GDP) Disrupts Peritoneal Membrane Function

    Growth of new, immature blood vessels on the peritoneal membrane is linked with ultrafiltration failure. Exposure to the GDP methylgyoxal (MGO) up-regulated both vascular endothelial growth factor (VEGF) and suppressed platelet-derived growth factor (PDGF) in vitro, potentially disrupting the balance of angiogenesis.

    Read the abstract » | (added 2020-03-16)

    Tags: Peritoneal Membrane, Ultrafiltration Failure, Methylgyoxal, Angiogenesis